The discipline that studies genetically determined inherited inter-individual differences (variability) in therapeutic response to drugs and susceptibility to adverse effects (Lerer 2002). The term pharmacogenetics was coined and introduced in 1959 by Friedrich Vogel in his article on “Moderne probleme der humangenetik”  published in the journal, Ergebnisse Inneren  Medizin und  Kinderheilkunde (Arranz and de Leon 2007;  Vogel 2007).

Lerer B. Introduction. In Lerer B, editor. Pharmacogenetics of Psychotropic Drugs. Cambridge: Cambridge University Press; 2002, 3-17.

Arranz MJ, de Leon J. Pharmacogenetics and pharmacogenomics of schizophrenia:

a review of last decade of research. Mol Psychiatry. 2007 Aug; 12 (8): 707-47.

Vogel F. Moderne probleme der humangenetik” Ergebnjsse Inneren Medizin und  Kinderheilkunde. 1959; 12: 52-125.

Thomas A. Ban
March 10, 2016