Donald F. Klein’s Third comment/question (Variations in neurotransmitter systems and supervening syndrome) on Martin M. Katz’s Depression and Drugs

In Katz’s view, do the several component neurotransmitter systems vary independently producing all possible combinations and manifestations? In that case there should be no recognizable syndromes or courses. Alternatively, are   certain neurotransmitter deviation   combinations   particularly   likely, thus giving the appearance of syndromes?

But if   certain   combinations   of deviances are somehow favored, how does that differ from the diagnostic syndrome formulation which accepts multi-causal impairments of a particular evolved adaptive function, as modified by adaptive backups, yielding a  particular somewhat variable, syndrome?

Donald F. Klein

June 12, 2914