Thomas A. Ban: Chlorpromazine after 50 years
Vimal K. Razdan’s comment
I agree entirely that even today the most reliable drug to control aggression is chlorpromazine. I use an injection of 100 mg of chlorpromazine with 50 mg of promethazine (Phenergan) intramuscularly, followed by intravenous diazepam as needed. This combined treatment has never failed to control aggression, however severe.
Vimal K. Razdan
November 3, 2016
Samuel Gershon: Ketamine, the "new" breakthrough in the trestment of Depression
Ken Gillman’s comment
You might be interested to know that one of the very first threads in the history of the story of ketamine started here in the backwoods of North Queensland at the Mackay Base Hospital (public hospital) some 20 years ago, when one of the anaesthetists decided he would try treating depression and tried to get a clinical trial going.
As you might imagine the local ethics committee was more or less a notional entity and had no competence to adjudicate on the matter. I advised them to consult with the Professor of neurology in Brisbane (and declined to be involved) and followed the developments. I have been interested in the ketamine story ever since
December 19, 2019