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Samuel Gershon: The Tacrine paradigm


Hector Warnes’ comment


        Tacrine (Cognet) is still in use as a cholinesterase inhibitor that augments the nicotinic receptors in the brain as well as the number of neurotransmitters. It has not been withdrawn from the market in some countries. You can check it out in Google. I do agree with Professor Gershon that some drugs like ketamine have been introduced without enough research or clinical trials. I really do not have any experience with ketamine or tacrine. I have used mostly rivastigmine (Exelon Patch from Novartis) in dementia. I understand that ketamine is used by veterinary doctors as an anesthetic for horses and is used by the "drug culture" as a psychedelic with mood elevating properties


July 16, 2020