Donald F. Klein’s Response to Martin M. Katz Reply to his 4th Comment on Katz’s Depression and Drugs

Katz and I agree that it is best to defer judgment on the knotty area of syndromes, neurotransmitters, and distinct neurotransmitter behavioral effects while awaiting relevant findings.

During theoretical mysteries various approaches are tried, hoping, as researchers do, that there may be a payoff.

Nonetheless, Katz clairvoyantly states "What is needed...is to set aside the syndrome concept ... first apply  ... the same level of precision in describing...psychopathology, applied to the measurement of the neurochemistry".

How can Katz be so sure about "What is needed"?

Donald F. Klein
November 13, 2014